Vendor testing comparison on purity reports versus independent lab assays

Posted by quietfox94 in Vendor Reviews and Sourcing

Hey everyone I have been looking closely at the certificates of analysis provided by various suppliers lately. I noticed some vendors use third party labs while others rely on internal testing which got me wondering about the variance in purity numbers. Has anyone here sent their vials to an independent facility for mass spec analysis to verify what is on the paper? I am trying to gather data on how often independent results match the stated vendor specs.

7 Comments

quietfox94

That is what I figured as well. Have you noticed any specific labs that seem to be the gold standard for these assays?

clinicalhead

Honestly most internal certificates are just glorified marketing sheets printed in house.

protocol21

You guys are overthinking it completely. Just pick a popular supplier with decent reviews and save your money instead of paying for extra lab tests.

vialfiles

Speaking from experience the group testing drives organized on specific forums are usually the cheapest way to get real mass spec data on current batches.

vialx84

Trusting a supplier without independent verification is a great way to ruin your entire research project. Always verify everything yourself if you want actual reliable data.

molarstack35

Spot on with that observation. I always look for a verifiable HPLC report from a recognized third party lab before making any decisions.

researchguy4

Group testing projects have saved my lab so much time and cash over the last year. Highly recommend looking into those community efforts.